Biologic materials like bovine pericardium are widely used in cardiovascular, neurosurgical, and soft tissue reconstruction. However, one critical step in preparing these tissues for human use is decellularization — the process of removing native cells while preserving the extracellular matrix (ECM). This article explains how decellularization works, why it matters, [...]

Biologic materials like bovine pericardium play a vital role in cardiac surgery — from patching septal defects to reconstructing valves and vessel walls. However, choosing the right material involves evaluating several key factors: thickness, processing method, preservation format, and performance under pressure. This guide summarizes everything surgeons need to make [...]

In neurosurgery, one of the critical challenges following cranial or spinal procedures is the safe and effective closure of the dura mater — the tough outer membrane that surrounds the brain and spinal cord. Damage to or removal of this layer can expose patients to risks such as cerebrospinal fluid [...]

Biologic materials like bovine pericardium are essential in modern surgery — offering natural strength, flexibility, and compatibility with human tissue. However, their effectiveness heavily depends on how they are stored and preserved. Improper storage can degrade tissue structure, compromise sterility, or reduce surgical performance. This article explores the three most [...]

Biological tissue engineering has rapidly evolved over the last decade, combining biology, materials science, and biotechnology to create safer, smarter, and more effective medical grafts. As we move through 2025, new innovations are reshaping the way biologic tissues — like bovine pericardium — are processed, preserved, and applied in clinical [...]

Biologic grafts such as bovine pericardium are widely used in cardiovascular, reconstructive, and neurosurgical procedures. While strength, flexibility, and handling are critical factors, low immunogenicity — the ability to avoid triggering an immune response — is equally important for the long-term success of the graft. In this article, we explain [...]

Bovine pericardium has become a trusted biological material in modern surgery — particularly in cardiac, vascular, and soft tissue reconstruction. To maintain its mechanical integrity and biocompatibility, it’s crucial to handle and store this tissue correctly. Below are the best practices for surgeons, surgical nurses, and hospital staff to ensure [...]